| abstract |
A compound of formula (I), wherein X is CF3, C2F5, 2-benzothiazole, CF2CONHR6, CONHR6, wherein R6 is CH2C6H5, CH2(4-iodophenyl), CH3, (CH2)2OCH2C6H5, CH2-2-benzimidazole, CH2-(3,4-methylenedioxybenzene), CH(CH3)C6H5 or CH(CH2CH3)C6H5; or X is 2-benzoxazole-R7 wherein R7 is H, 4-CH3, 5-CH3, 6-CH3 or 7-CH3; R1 is H, CH3 or CH2CH3; R2 is CH2CONH2, CH2CH2CONH2, CH2-thiazole, CH2CON(CH3)2, CH2CO-(pyrrolidino), CH2CH(CH3)2 or CH2C6H5; R3 is Et, CH(CH3)2, C(CH3)3, adamantyl, CH2C(CH3)3 or C(CH3)2CO2H; and R20 is COCH2C(CH3)3, COCH2CH2C6H4OH, COCH2CH(CH3)2, CO2C(CH3)3, CONHC(CH3)3, COCH2N(CH3)2, CO(CH2)3CO2H, CO-(S)-CH(NH2)C(CH3)3, CO-(S)-CH{NHC(O)O-C(CH3)3}C(CH3)3, CO-(S)-CH{NHCO(CH2)5NHC(O)OC(CH3)3}C(CH3)3 or CO-(S)-CH{NHCO(CH2)5NH2}C(CH3)3. These compounds are useful for the treatment of human cytomegalovirus infection. |