| abstract |
Remedies for bladder disorders capable of extending the vesical mucosal epithelium and/or repairing the vesical mucosa and thus exerting excellent therapeutic effects on bladder disorders, in particular, non-bacterial intractable bladder disorders. These drugs are prepared by compounding remedies for bladder disorders with hyaluronic acid and/or pharmaceutically acceptable salts thereof, preferably those having the properties as will be specified hereinbelow, in such an amount as to be efficacious in extending the vesical mucosal epithelium and/or repairing the vesical mucosa, preferably from 0.2 to 0.6 % by weight based on the whole preparation: (A) containing not more than 0.03 EU (endotoxin unit)/10 mg of endotoxins; (B) containing not more than 0.01 % of sulfur when determined by coulometric titration; (C) containing not more than 20 ppm of iron; (D) containing not more than 0.1 % of proteins; and (E) having a weight-average molecular weight of at least about 500,000. |