Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f32d9f9147c718b8216df8877479641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa3ad7dd8199ba2396864292e57299b9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-295 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
filingDate |
1997-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c15e52b2ee5d81b106a9588032d6bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5769fe7f3f84ebdc8cdb29ef38abb596 |
publicationDate |
1998-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9829109-A1 |
titleOfInvention |
Methods and compositions for identification of autoantigens |
abstract |
Autoantigens with immunocryptic sites may be cleaved at particular sites in the presence of metals such as iron or copper and reactive oxygen species to produce antigenic protein fragments which are useful in diagnosing autoimmune diseases. Substances that interfere with fragmentation process may be used to treat autoimmune diseases and the fragments may be used to tolerize patients. Non-enzymatic proteolysis according to the invention has wide applicability as a biochemical tool. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9370524-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8946295-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163764-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005005458-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8883148-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846039-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2295059-A3 |
priorityDate |
1996-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |