http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9827107-A8
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3ba6f026ef5776ed3a79d2944f81a87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da1b4a7e9830009fa307c2a744d49a7b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
| filingDate | 1997-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad2578da34e7758c87b690b36d65088a |
| publicationDate | 2000-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9827107-A8 |
| titleOfInvention | Method of coupling polysaccharides to proteins |
| abstract | A novel method of covalently coupling polysaccharides to other biopolymers is provided, using an amino-thiol linker represented by formula (1): H2N-[(CH2)m-CHR?1-CR2R3-A]¿q-CHR?4-(CHR5)¿p-CHR6-S-R7 wherein A is a direct bond or a group having the formula -{Z-(CH¿2?)m-CHR?1-CHR2R3}¿nZ-, m is an integer from 0 to 5; n is an integer from 0 to 3; p is an integer from 0 to 2; q is the integer 0 or 1; R1 is hydrogen or C¿1?-C6 alkyl, optionally substituted by amino, hydroxyl, carboxyl, C1-C4 alkoxycarbonyl, carbamoyl, mono- or di(C1-C4alkyl)carbamoyl or N-(α-carboxyalkyl)carbamoyl, or, if m ≠ 0, R?1¿ is hydroxyl, amino or peptidylamino; R?2 and R3¿ are independently hydrogen or C¿1?-C4 alkyl, or together form an oxo group; R?4¿ is hydrogen, C¿1?-C4 alkyl, carboxyl, C1-C4 alkoxycarbonyl, carbamoyl, mono- or di(C1-C4 alkyl)carbamoyl or N-(α-carboxyalkyl)carbamoyl; R?5¿ is hydrogen, methyl, hydroxy or C¿1?-C7 acyloxy; R?6¿ is hydrogen or methyl; R7 is hydrogen or a thiol-protecting group or a group having the formula -S-CHR?6-(CHR5)¿p-CHR?4-[A-CR2R3-CHR1-(CH¿2)m]q-NH2; and z is imino, methylimino, oxygen or sulphur. |
| priorityDate | 1996-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.