| abstract |
Dihydrophenazinecarboxylic acid derivatives represented by general formula (I) wherein R1 represents hydrogen, linear or branched alkyl, etc.; R?2 and R3¿ each represents hydrogen, 3-methyl-2-butenyl, etc.; and R?4 and R5¿ each represents hydrogen, alkyl, alkenyl, alkynyl, aralkyl, aryl, hydroxy, alkoxy, aryloxy, aralkyloxy, halogeno, nitro, cyano, alkylsulfonyl, arylsulfonyl, alkylcarbonyl, arylcarbonyl, etc., exclusive of the case where both of R?4 and R5¿ are hydrogen. The dihydrophenazinecarboxylic acid derivatives are excellent in the inhibition of glutamic acid toxicity. |