http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9821224-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5be1d27acf8a63f82dff0177ddaf7fae |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 1997-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1b7adc76599b32318d1287b4ce60b3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d8bcf546813ac78b201b15f367123a1 |
| publicationDate | 1998-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9821224-A1 |
| titleOfInvention | The cloning of duffy blood group antigen |
| abstract | The major subunit of the Duffy blood group antigenic system, gp-Fy protein, has been isolated, as have two variants, gp-Fyα and/or gp-Fyβ, which are produced from the Duffy FY gene by a differential splicing mechanism. gp-Fy protein contains the receptor by which P. vivax enters red cells and causes malaria. gp-Fy protein has therapeutic value in the prevention of malaria and in the regulation of erythrocyte, neural and renal functions and can be combined with physiologically acceptable diluents to yield a therapeutic agent suitable for these purposes. Peptides corresponding to a portion of gp-Fy protein that contains the receptor also have been synthesized. gp-Fy protein and derived peptides have utility in the production of therapeutics, e.g., antibodies, complementary peptides, etc., which are also useful to treat malaria and regulate essential erythrocyte, neural and renal functions. Also provided are nucleic acid primers and probes which specifically bind to or hybridize with portions of the FY gene or DNA or RNA derived therefrom for detecting the presence of gp-Fyα and/or gp-Fyβ nucleic acids in tissues samples. Methods for detecting Duffy protein expression, i.e., differential expression of gp-Fyα and/or gp-Fyβ proteins are provided. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016144642-A1 |
| priorityDate | 1996-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 851.