| abstract |
The present invention is directed to method of disinfecting a contact lens with an ophthalmically safe disinfecting aqueous solution comprising about 2.0 to about 8.0 ppm of a bis(biguanide) having formula (I), wherein R?1 and R4¿ are independently selected from the group consisting of branched or unbranched alkyl having 4-12 carbon atoms, ether or thioether radical having 4-12 carbon atoms, or cycloalkyl or cycloalkyl-alkyl radical having 5-12 carbon atoms; R?2 and R3¿ are independently selected from the group consisting of hydrogen, alkyl having 1-1 carbon atoms, alkoxyalkyl having 1-12 carbon atoms, or cycloalkyl or cycloalkyl-alkyl having 5-12 carbon atoms; R?6 and R7¿ are independently selected from the group consisting of hydrogen and alkyl radical having 1-6 carbon atoms, and A in said formula is selected from the group consisting of a divalent alkyl, alkyloxyalkyl, or alkylsulfide radical each having 4-12 carbon atoms. The invention is also directed to a method of cleaning and/or disinfecting a contact lens within a minimum soaking period that is not more than about 75 minutes. |