| abstract |
A local anesthetic for external use is prepared by blending a) an active ingredient selected from lidocaine, prilocaine, and pharmaceutically acceptable salts thereof, b) a percutaneous absorption accelerator, c) ethanol and/or isopropyl alcohol, and d) water such that the blending ratio of ethanol and/or isopropyl alcohol to water is preferably 0.5 to 1.2 in weight, and pH is preferably adjusted to be 6.0 to 8.5. Thus the percutaneous absorption type local anesthetic for external use is provided, which is conveniently used when it is applied and peeled off, which is applicable to a broad skin surface, and which is excellent in percutaneous absorption and quick efficacy as well as excellent in stability. |