| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0195c17403345cdb4758db687220814
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d69247c5cf5ae0f110ece6b75e13612
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b6863b5da379abae9fbf08e1eb16546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4afaa7cff2577d18c0c0ce5aa491868c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1fa817ab08d06bd2e1d2154392bd08d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_041a0a41776c2e5c9c2d459b7b3e74c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8838cf92ac37ccc5b4f7f07661f4505c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-08 |
| filingDate |
1997-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17e04079fa324fd26e595f07695696e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d98dffd64a0260cd87fa7d827d12e03f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62cbe17c931ff1e5cd0808496e8b8fcf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1360835d4dbdd0c376f58b46e1ec7cd3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48c4921eebe6706cd605b3fed6c56262
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0c524479d6d11e2798cb3d1987a2f3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ee428d549620d8e30629a415d9aa068 |
| publicationDate |
1998-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9813381-A1 |
| titleOfInvention |
Modified physiologically active proteins and medicinal compositions containing the same |
| abstract |
Modified physiologically active protein which can be produced by reacting a physiologically active protein having a molecular weight falling within the range of from 1 x 103 to 2 x 105 and carrying at least one Gln residue serving as the substitute of transglutaminase with a branched ligand consisting of an amino acid derivative having a lower binding affinity to the asialoglycoprotein receptor located on hepatic parenchymal cells than that to asialoorsomucoid and carrying an amino group and a galactose (Gal) or N-acetylgalactosamine (GalNAc) group serving as the substrate of transglutaminase in the presence of a transglutaminase originating in a microorganism to thereby form an amide bond between the η-carboxyamide group of the glutamate residue in the physiologically active protein and the terminal amino group in the branched ligand; and a process for producing the same. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9127276-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015168589-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015168618-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9163239-B2
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6267957-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9145558-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4206213-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014179627-A2
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021074772-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018014041-A2
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926556-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4119569-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3845547-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9714421-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11732265-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017053722-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019140452-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3524680-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019217527-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299736-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9181550-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11312964-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017079745-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557137-B2 |
| priorityDate |
1996-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |