http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9812218-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd72d510758ebd143301580192216186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634715a790f7ef0163a61e9f364bebcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46ef028c082758532ac8fd9aa9c3b7b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d400c6dd2075d40860422d4e9231828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2d9f42354aaadf76602022078988e5c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate | 1997-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7972deed041ac9895b9926a628d492ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80bcc15ad58cc05339019de593ee6587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b6a56b134bfca05eea79ad86713017f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd4b7b42695baa355faf517db681e162 |
| publicationDate | 1998-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9812218-A1 |
| titleOfInvention | Tri- or polysulphide containing peptides having immunomodulating activity |
| abstract | A physiologically active tri- or polysulphide linked peptide homo- or heterodimer or cyclised monomer, derived from one or more monomers of formula (I): A-R2-R3-B (SEQ ID NO:1) wherein R2 is a residue of an amino acid selected from proline (Pro), isoleucine (Ile), alanine (Ala), tyrosine (Tyr), pipecolic acid (Pec), threonine (Thr), arginine (Arg), glycine (Gly), or R8, R3 is R8, and each R8 is independently an amino acid residue of formula (II) or formula (III), wherein each of R5 and R6 is independently selected from H, alkyl, e.g. methyl, aryl and alkoxy, n is selected from 0, 1, 2, 3 and 4, and m is selected from 0, 1, 2, 3 and 4; the entire peptide sequence of each monomer containing 3 to 30 amino acid residues; the dimer being formed by linking of the sulphide group of at least one R8 group of one monomer to the sulphide group of an R8 group of the other monomer via an -(S)p- wherein p is an integer of at least 1, so that a trisulphide or polysulphide link is provided, and the monomer being cyclised by linking of the sulphide group of one R8 group to the sulphide group of another R8 group via an -(S)p-, wherein p is an integer of at least 1, so that a trisulphide or polysulphide cyclising link is provided, is absorbable by the epithelial cell lining in a mammal resulting in a modulated immune response and thereby a therapeutic effect against disease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9948865-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114276411-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10973920-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6288250-B1 |
| priorityDate | 1996-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 332.