Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a486ad2814625a10b71c7439f280a902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e7b36f15372b723929cf917d692e4f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6da8ad1218af48a02e7d5e93ce1d5b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82a45d0fb65c4375692fc5753f1757cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebdd8cdbe2c277a3b3840873fe1e4bec |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 |
filingDate |
1997-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300eccf83e9941e8131b40ec07c23061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37f999bde9b84604456b1e7da8337f4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb07eb88121cdbfcafc90d560edb51a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_511619721244dead4905987d1074912b |
publicationDate |
1998-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9812188-A2 |
titleOfInvention |
Process for producing simvastatin |
abstract |
A process for manufacturing simvastatin is provided comprising reacting lovastatin with an organic boronic acid to produce a derivative of lovastatin with a hemiboronate group attached to the C-4 carbon of the pyranyl group, methylating the 2-methylbutyryloxy group on the lovastatin derivative to form a 2,2-dimethylbutyryloxy group on the lovastatin derivative and thereafter removing the hemiboranate group to produce simvastatin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6384238-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0032585-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6562984-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6331641-B1 |
priorityDate |
1996-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |