abstract |
An in situ gel forming pharmaceutical composition for local administration to a target organ in the body, said composition essentially consisting of a water solution containing one or more aggregate forming surfactants, one or more gel forming water soluble polymers, a drug and optionally excipients, said drug having lipophilic properties, as it binds stronger to the aggregates of surfactants than to water, whereby its release from the in situ forming gel to the target organ occurs slowly. |