| abstract |
Chromone derivatives represented by general formula (I) or pharmaceutically acceptable salts thereof and nerve cells death inhibitors containing the same as the active ingredient wherein R represents carboxyalkyl, carboxyalkenyl, alkoxyalkyl, alkoxycarbonyl, alkylthioalkyl, alkylsulfinyl-alkyl, alkylsulfonylalkyl, alkylsulfonyl, alkylcarbonyloxy-alkyl, alkoxycarbonylalkyl, alkoxycarbonylalkenyl, branched alkyl, aliphatic acyl, alkoxycarbonyl, optionally substituted carbamoyl, optionally substituted thiocarbamoyl, optionally substituted 1-piperidinylcarbonyl, optionally substituted 1-pyrrolidinylcarbonyl, optionally substituted 1-piperazinyl-carbonyl, optionally substituted morpholinocarbonyl, optionally substituted benzenesulfonyl, alkenyl, 2-acetoxy-2-methylpropionyl, benzoyl, alkoxybenzoyl, nitrobenzoyl, acetoxybenzoyl, aminobenzoyl, morpholinomethylbenzoyl, thiophenecarbonyl, furoyl, pyridinecarbonyl, phenoxycarbonyl or diphenoxyphosphoryl. |