| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4f5989502f3c393ca2956f576e7e1e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbc71d364a516dc36f9b39075dac8bda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c12bb47076fd4337af2606d807cd95e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96758fbd76a71e0071a8f42817987b24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2663d0d3fb72f0e8f10c85e6e9458030 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S623-926
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0068 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M5-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M5-32 |
| filingDate |
1997-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68c52a6ac2f81f362f0ad4d25be8f067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e2cadca431fe3991f16ab56eea1ff5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e02bf3cad7bd180af15070793428db05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c953375c4df68ca8748614b85a496b61 |
| publicationDate |
1998-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9808482-A3 |
| titleOfInvention |
Polymeric coating for a surface exposed to blood |
| abstract |
The aggregation of platelets on the surface of a foreign body exposed to the flowing blood of a living being (such as plastic tubing, a balloon or the end of a catheter surgically inserted in a blood vessel, a stent implanted therein or synthetic grafts, which surface normally promotes such platelet aggregation to form a coating firmly affixed to that surface which would restrict the flow of blood past that surface or to form a blood clot detachable from that surface), is inhibited by a gas permeable coating on the surface of a physiologically acceptable polymer as which contains dissolved or dispersed therein a nitrosyl-containing organometallic compound, such as sodium nitroprusside, which is protected from diffusion from the coating and from direct contact with the blood and which slowly decomposes at the body temperature within the coating and in so doing releases a platelet aggregation-inhibiting amount of nitric oxide which diffuses from the coating during the period when platelet aggregation by the surface of the foreign body would be promoted in the absence of the polymer coating. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9403851-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9403852-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8981139-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8591876-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9526738-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8956658-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8282967-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8962029-B2 |
| priorityDate |
1996-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |