| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0083 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate |
1997-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff90edd0df32f715b5e0c13ad981b14d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e6c18cf41781782e61374388dcbc6b |
| publicationDate |
1998-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9805679-A3 |
| titleOfInvention |
Mixed agonists of the progesterone receptor and assays therefor |
| abstract |
A third class of PR-ligand (i.e. mixed agonist) is identified which induces a progesterone receptor conformation distinct from that induced by a PR agonist or antagonist. PR mixed agonists exhibit partial agonist activity which is influenced by cell context. These compounds provide useful pharmacological profiles for treating progesterone related diseases and/or conditions. Assays are provided to screen for PR mixed agonists. Molecular designs are provided to convert a PR antagonist to a PR mixed agonist. |
| priorityDate |
1996-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |