| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a58c933c1c0add470d47fb772f5a7f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2641d82cf1d38dd84e453bbd60f30cc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1997-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0276ff7209c26ffd32108bcbcd310e01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c315cf461113447a9b194f45d850e825 |
| publicationDate |
1998-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9803652-A2 |
| titleOfInvention |
P300/cbp-associated transcriptional co-factor p/caf and uses thereof |
| abstract |
The present invention provides a purified protein designated P/CAF having a molecular weight of about 93,000 daltons as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis under reducing conditions and which acetylates histones and which also binds to the p300/CBP cellular protein. The present invention further provides a nucleic acid encoding the P/CAF protein as well as a vector containing the nucleic acid and a host for the vector. A purified antibody which specifically binds the P/CAF protein is also provided. Also provided are methods of screening for compounds that inhibit or stimulate the transcription modulating and histone acetyltransferase activity of P/CAF and p300/CBP. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7407748-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9960407-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919276-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6864054-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005021025-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1222308-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6692929-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9920752-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110170052-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1222308-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7892818-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7531320-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004085646-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02070675-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9961608-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9857982-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0200864-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9857982-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6890709-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7396643-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9961608-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6376215-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02070675-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113736780-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0200864-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005021025-A2 |
| priorityDate |
1996-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |