Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0221cfbb710aca0e7f791b87705949d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2427716fc69ab2e2d3493d8d6385c6aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b22263221cba5fcde82f61dbe007f286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b818cb56b5588f63bb26b10609e8a7e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-75 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-00 |
filingDate |
1997-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2a0767d6dc8428fde9d4fb000791d1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_576cab8adad8a4e49e9d11746ebf5df7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4b9dacdf0ca19b16872b02f4960d285 |
publicationDate |
1998-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9802567-A2 |
titleOfInvention |
PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM) |
abstract |
The present invention describes a process wherein Acremonium is used as a suitable and convenient organism for the production of N-acylated cephalosporin derivatives. In the process of the invention, a recombinant, acyltransferase-expressing Acremonium strain is cultured in the presence of a suitable acyl side chain precursor. Optionally, the acyltransferase-expressing Acremonium strain further does not express hydroxylase and/or acetyltransferase activity. The N-acylated cephalosporin derivative is recovered without contaminating α-aminoadipyl cephalosporin compounds. The thus recovered compound subsequently may be deacylated via chemical or enzymatical means. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012032040-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021054545-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0078989-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115175992-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2165276-A1 |
priorityDate |
1996-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |