| abstract |
Antibacterial drugs exhibiting potent antibacterial effects against various bacteria and high safety, which comprise compounds of general formula (1), or salts of the compounds or hydrates thereof: wherein R?1 and R2¿ are each hydrogen or alkyl; n is an integer of 1 to 3; R3 is alkyl, alkenyl, halogenoalkyl, cyclic alkyl, aryl, heteroaryl, alkoxyl or alkylamino; R4 is hydrogen or alkylthio; R5 is hydrogen, amino, hydroxyl, mercapto, halogenomethyl, alkyl, alkenyl, alkynyl or alkoxyl; X1 is halogeno or hydrogen; A is nitrogen or (II); X2 is hydrogen, amino, halogeno, cyano, halogenomethyl, halogenomethoxyl, alkyl, alkenyl, alkynyl or alkoxyl; and Y is hydrogen, phenyl, acetoxymethyl, pivaloyloxymethyl, ethoxycarbonyl, cholyl, dimethylaminoethyl, 5-indanyl, phthalidyl, 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl, 3-acetoxy-2-oxobutyl, alkyl, alkoxymethyl or phenylalkyl. |