| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90b2a59fd0a4b38f6d8a56745cb283a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68355bb7e2bfbb8d08bdd04258d0aaad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13dc24428f765c25551704b6519b98ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1491f675b8b0bee6da136cfa0cdf3703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bb49c4d3b3e0935fd505e6909129998 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-94 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 |
| filingDate |
1997-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c51029585afa62446691eb30ef9b9023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01d21c966f7e82ba020df677c8093298
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14f3889bfae4a03b05d231fa48d0a94f |
| publicationDate |
1998-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9800715-A2 |
| titleOfInvention |
Method of assaying compounds which affect the activity of g protein-coupled receptors based on measurement of receptor oligomerization |
| abstract |
This invention is a new method of assaying compounds that modulate the activity of G protein-coupled receptors based on measurement of changes in the relative proportions of monomeric to multimeric receptor polypeptides. More specifically, techniques are described herein which permit the prediction of the pharmacological efficacy of drug candidates based solely on the ability of the candidate compounds to alter the ratio of receptor monomer to homo-oligomeric forms of the receptor. This method provides a novel means of assaying compounds as potential therapeutic drugs at G protein-coupled receptors which is greatly simplified and more generally applicable than existing methods. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10709763-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5985584-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6368848-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7297503-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10957723-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0246763-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9837413-A1 |
| priorityDate |
1996-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |