| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70ac79a3e3011264aefb62007de25117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c11d61eb758111c4e78e8ad81eef2fcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cac4c69cf81a5e5b11df7e702007c70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94d9556eebfc56ba4373a9fd974ba340 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate |
1997-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40c0f5dc26b43a8f63b0bc5caf44437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d603ada6c746a0f031039f6ddeff8aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e87c4c48e50b009e56249b205cad69 |
| publicationDate |
1998-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9748815-A3 |
| titleOfInvention |
Method for enhancing gene transfer |
| abstract |
The present invention provides a method for optimising gene transfer into hematopoietic stem cells (HSCs) by contacting the cells with hydroxyurea prior to gene transfer to induce HSCs in G0 into active cell cycle. This method is useful for treating patients suffering from a disease that is suitably treated by gene therapy or involves hematopoietic cells. A method is also provided for enhancing the efficacy of bone marrow transplantation by administering hydroxyurea to increase HSC yields. |
| priorityDate |
1996-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |