abstract |
Compounds are described of general formula (I) in which Y and Q are the same or different and are hydrogen atoms or C1-6 alkyl groups, optionally substituted by 1-4 hydroxy or 1-4 R3O2CCH2CH2CO2- groups, where R3 is a hydrogen atom or a C¿1-6? alkyl group which may be straight or branched and saturated or unsaturated, and R?1 and R2¿ are the same or different and are C¿1-6? alkyl groups, which may be straight or branched and saturated or unsaturated, and solvates and prodrugs of these compounds and the salts of compounds in which R?3¿ is a hydrogen atom. These compounds can be used in the treatment of diseases caused by or resulting in metabolic dysfunction and/or energy deprivation, such as diabetes, acute starvation, endotoxemia, sepsis, systemic inflammatory response syndrome and multiple orgen dysfunction syndrome. |