| abstract |
Novel pyridocarbazole derivatives having a highly selective cyclic GMP-phosphodiesterease (hereinafter referred to simply as cGMP-PDE) inhibitory effect; a process for producing the same; preventives and/or remedies for pulmonary hypertension, ischemic heart diseases or diseases against which cGMP-PDE inhibitory effects are efficacious, characterized by containing as the active ingredient at least one of these derivatives; and intermediates useful for producing the pyridocarbazole derivatives. |