http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9743448-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56666880a5e2b7703e98a4f9b2d9daf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95e9f4ca2ee84e15265faf0e3a9a3455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0badac272351868667128d3c68c7b4fe |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 1997-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9e350842382f9b050a43d83af2e2abe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6dbaf66a5c36143c397fa48a6ba87a1 |
| publicationDate | 1997-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9743448-A2 |
| titleOfInvention | Analysis of expression of rat cytochrome p450 isoenzymes and phase ii conjugating enzymes |
| abstract | Hepatocyte culturing system, primer sets and an analytical method for selectively detecting and quantitatively assessing the levels of mRNA expression of the major isoenzymes of cytochrome P450 (CYP450 1A1, 1A2, 2B1/2, 2C11, 2E1, 3A1, 3A2 and 4A1), fatty acyl-CoA oxidase (FACO) and select Phase II conjugating enzymes (UDPGT, GST and ST) in the rat using specific 5' and 3' oligonucleotide primers and reverse transcriptase-polymerase chain reaction. The method closely reproduces the expression obtained from rat liver tissue following treatment with the same enzyme inducers. Constitutive and inducible expression was maintained by resuspending, culturing and then overlaying adult rat hepatocytes with an extracellular matrix such as Matrigel®. |
| priorityDate | 1996-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 767.