Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4f206270f06dc642da25b894b96dd06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-74 |
filingDate |
1997-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3590a736e1a5068ce05accc7e4e6719 |
publicationDate |
1997-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9738310-A1 |
titleOfInvention |
Method for detecting organ allograft rejection and uses thereof |
abstract |
This invention provides for a method for monitoring allograft rejection in a transplant recipient which includes: (a) obtaining peripheral blood lymphocytes from the recipient; (b) incubating the lymphocytes with at least one synthetic allopeptide which corresponds to an immunogenic hypervariable epitope of a mismatched donor HLA-DR antigen under suitable conditions; and (c) contacting the incubate with a marker for T-cell activation to determine whether or not the incubate contains activated T-cells, thereby monitoring allograft rejection in the recipient. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0165256-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0024777-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2375395-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6783936-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2372506-A1 |
priorityDate |
1996-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |