| abstract |
A method for administration of botulinum toxin, includes the steps of (a) selecting at least one neuromuscular blocking agent having a duration of activity shorter than neuromuscular blocking activity of botulinum toxin; (b) selecting at least one muscle of a muscle group; (c) intramuscularly injecting the selected agent into the selected muscle; (d) observing muscle relaxation in both the selected muscle and other non-selected muscles in the muscle group to determine spill-over, muscle tone and balance; (e) repeating steps (b) - (d) until a final muscle selection is found; and (f) intramuscularly injecting botulinum toxin into the final muscle selection. |