http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9733575-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3a790b883cd45182f9cd8618f1c92fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e544a582266040c77f2272e9c9e176f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f2c8111feced35067b74fa761712d7a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-222 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-222 |
filingDate | 1997-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_125a48f551e3467c55477ae68463ecca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f5111509004a3018e49bfb476cdb0f4 |
publicationDate | 1997-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9733575-A1 |
titleOfInvention | Use of tiamulin for preparing a drug for use as a cancer multidrug resistance reversion agent |
abstract | The use of the antibiotic tiamulin for inducing drug-sensitivity in chemotherapy-resistant human or animal tumour cells as soon as the tumour appears or during tumour development and/or cancer treatment, with a view to preparing a drug for treating malignant blood diseases and solid cancerous tumours in mammals, is disclosed. The cytotoxic activity caused by increased intracellular cancer drug retention may be studied by producing highly resistant tumour lines, i.e. mouse lymphoid leukaemia line P388 resistant to 25 νg/ml of adriamycin, rat hepatocellular carcinoma line AS30-D resistant to 5 and 10 νg/ml of colchicine, and human lymphoblastic leukaemia line CEM resistant to 0.45, 3.6 and 5 νg/ml of vinblastine. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2017426847-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11576930-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009106839-A1 |
priorityDate | 1996-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.