| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d31c026192cd9e37d7f0be24aaff4eeb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4260a256b5f28ea7d92b4c1f5b921d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_075ee2ec2f519cf729c47212365afa88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3fa1d805743ce81281cc18b80aa1665
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d35637bc8c6bb990ede16ab5e8a4136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2b2a78f239151ac54ca6979cf57d9fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1967972db65c14701a6feba96e0280e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b04cc1890fb9a374cd890950f21a2541 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1997-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fbc63cf193e5456629d5115d022124b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2ea6e3fcf9b037ea47cad2ee12db4ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d7245d405a739b3a8132e4845494285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3acba13ed361fbd9b8a9ad5001cbbca3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f7c4df16ad3a8fe0800846f31cae129
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f4bb5b615f02a237eef7289d9e5e23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90cb442426d0951d78ad39c2ecf3dabc |
| publicationDate |
1997-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9732998-A2 |
| titleOfInvention |
Materials and methods relating to the identification of a polymorphism associated with disease susceptibility |
| abstract |
The inventors have found a highly significant association between homozygotes (designated tt) for the less common allele t of the Taq1 VDR polymorphism and susceptibility to autoimmune infectious diseases such as tuberculosis, hepatitis B, leprosy, HIV-1. There is provided a method for the determination of an individual's susceptibility level to autoimmune disease or infectious disease which comprises obtaining a sample of tissue from the individual; obtaining from the tissue sample a test sample comprising nuclear material from cells of the tissue sample; establishing the individuals vitamin D receptor (VDR) genotype, namely establishing whether or not the individual is: homozygous or heterozygous for a less common allele of the gene for the vitamin D receptor (VDR) and wherein said less common allele of the VDR gene comprises the polymorphisms B and A in intron 8 of the VDR gene and the polymorphism t in exon 9 of the VDR gene; or homozygous for a more common allele of the VDR gene and wherein said more common allele of the VDR gene comprises the polymorphisms b and a in intron 8 of the VDR gene and the polymorphism T in exon 9 of the VDR gene and wherein the genotype in relation to the VDR is specifically associated with susceptibility level to one or more autoimmune or infectious diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006094103-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006094103-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0015836-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0015836-A3 |
| priorityDate |
1996-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |