http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9731655-A3

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filingDate 1997-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c79e0fa6e9e1bdc20865232b0e05d3e
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publicationDate 1997-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9731655-A3
titleOfInvention Modified cytokines for therapeutic use
abstract The object of the present invention is a new method and new products for the therapeutic use of cytokines. The method is based on the sequential administration of a component A (e.g. a biotinylated antibody) able to deliver onto a particular pathologic target a second component B (e.g. avidin), followed by a component able to bind the component B (component C) (e.g. biotin), conjugated with the cytokines. The method permits to increase the local concentration of the modified cytokines (C-cytokines) through the interaction with the 'artificial' receptor B and to cause a local biologic response mediated by 'natural' receptors.
priorityDate 1996-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.