| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b3c81bc92f0f06434ec1a01cd0137ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e72837de81999e7e72cb78d59d19e28 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate |
1997-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44123319b4020628c7552d638e0fc08f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fda86c8eb1ba711ecaadc1e1ae0a8f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b12e0a11fb82663e52a0bb2de1f938ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_383074eec033ea250038d6dc8f84c622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69f0cdd208c6551b5c2c7a54a4141fd1 |
| publicationDate |
1997-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9729757-A1 |
| titleOfInvention |
Rnase l activators and antisense oligonucleotides effective to treat rsv infections |
| abstract |
The invention concerns compounds and methods for treating infection with Respiratory Syncytial Virus. The compounds comprise an antisense portion, which is complementary to a normally single stranded portion of the RSV antigenomic strand (the mRNA strand), a linker and an oligonucleotide activator of RNase L, a ubiquitous non-specific RNase. The method comprises forming a complex of an activated RNase L and the antisense molecule. The application teaches methods of determining which portions of the RSV antigenomic strand are normally single-stranded. The application teaches that an antisense oligonucleotide having the sequence of residues 8281-8299 of the RSV genome is particularly useful to practice the invention and provides in vitro results superior to those obtainable with the conventional drug of choice, ribavirin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1393745-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7407944-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7517862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7276489-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7749975-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9028845-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7812000-B2 |
| priorityDate |
1996-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |