http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9729090-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 |
filingDate | 1997-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc557d616b3f088132e5598225cedf2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc8030f7b02cff8b4409a35d3f22637f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7331cf12e1b35028d3b541ab5114e6b |
publicationDate | 1997-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9729090-A1 |
titleOfInvention | Bis-(heteroarylmethoxyphenyl)cycloalkyl derivatives, their preparation and their use as inhibitors of leukotriene biosythesis |
abstract | Compounds having structure (I), where m is an integer of from one to nine; n is an integer of from one to four; W is selected from unsubstituted quinolyl, benzothiazolyl, or quinoxalyl, or quinolyl, benzothiazolyl, or quinoxalyl substituted with one, two or three substituents selected from the group consisting of halogen, C1-6 alkyl, and C1-6 alkoxy; X is absent or is selected from the group consisting of (a) C1-6 alkylene; (b) C1-6 alkenylene; and (c) C1-6 alkynylene; Y is one to four substituents independently selected from halogen, C1-6 alkyl, and C1-6 alkoxy; Z is selected from the group consisting of (a) COB; (b) C(R2)2-O-N=A-COB; and (c) C(R2)=N-O-A-COB where A is C¿1-6? alkylene, and B is selected from the group consisting of (a) -OH; (b) -O?-M+¿ where M is a pharmaceutically acceptable cation; (c) -OR6 where R6 is hydrogen or alkyl of one to six carbon atoms; (d) -NR6R7 where R6 is as previously defined and R7 is selected from the group consisting of hydrogen, alkyl of one to six carbon atoms, hydroxy, and alkoxy of from one to six carbon atoms, or R?6 and R7¿, together with the atom to which they are attached, form a ring of five to eight members containing one optional heteratom selected from N, O and S; and (e) -O-D where D is a metabolically cleavable group, are inhibitors of leukotriene biosynthesis. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8883858-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8883857-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9061983-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8987337-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9622988-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8895626-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9585848-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9585847-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9610257-B2 |
priorityDate | 1996-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 327.