| abstract |
The invention relates to cobalt compounds in which divalent or trivalent cobalt is complexed with water soluble tetradentate Schiff's bases. The tetradentate Schiff's bases preferably contain two nitrogen atoms and two oxygen atoms as coordinating atoms. The compounds can contain polypeptide or nucleic acid targeting moities and can be used to inhibit enzymes such as thrombin and to inhibit zinc finger proteins. |