Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5d1de0cb099ee72980dadb3b90d66d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ff073ef7069a9d4d1acc95feaa3aa35 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-103 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6464 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21069 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
1996-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4aaf27ab9639b5bdb38a4e6c1706e7b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60897acc9804a0ceaf64c21fafe96863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c06976d5c92eeebc9787bb409e80d35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3173e7e975848c905f91e24a315c1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc7223d5636077dcbeb6160d3deff72e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e75dedf6834735b328151b0d57dffe58 |
publicationDate |
1997-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9720043-A1 |
titleOfInvention |
Protein c production in transgenic animals |
abstract |
Methods for producting protein C in transgenic non-human mammals are disclosed. The protein C is modified at the two-chain cleavage site between the light and heavy chains of protein C from Lys-Arg to R1-R2-R3-R4 where R1 through R4 are individually Arg or Lys. DNA segments encoding modified protein C are introduced into the germ line of a non-human mammal, and the mammal or its female progeny produces milk containing protein C expressed from the introduced DNA segments. The protein C expressed from the introduced DNA segments has anticoagulant activity when activated. Non-human mammalian embryos and transgenic non-human mammals carrying DNA segments encoding heterologous protein C are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9903981-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6489296-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6743426-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6156734-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6767539-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6504081-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6270764-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6008199-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6344197-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6372213-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7638123-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7204981-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6395270-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7087578-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02055110-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6436397-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6071514-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7615537-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6815533-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6268344-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6630137-B1 |
priorityDate |
1995-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |