abstract |
Compounds of formula (I), wherein X is O or S. The compounds of this invention are useful for the inhibition of the replication of Human Immunodeficiency Virus-1 (HIV-1) and reverse transcriptase (RT) mutants thereof, in vitro and in vivo. The compounds are useful in the therapeutic or prophylactic treatment of diseases caused by HIV-1 and RT mutants thereof, such as acquired immune deficiency syndrome (AIDS). |