| abstract |
Compounds represented by general formula (I) or their pharmaceutically acceptable salts which are useful as a selectin inhibitor and appropriately usable in the treatment or prevention of various inflammations, for example, inflammatory dermatitides such as atopic dermatitis, contact hypersensitivity and photosensitivity, autoimmune chronic diseases such as rheumatoid arthritis and chronic thyroiditis and ischemia/reflow disorders; wherein X1 represents an atomic group represented by formula (1), (2) or (3); R1 represents branched long-chain alkyl; R2 represents -CONHR3, carboxy or hydrogen; n is an integer of 0, 1 or 2; and R3 represents lower alkyl or phenyl. |