| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1966444097863eaf8cc99198286323e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B05D7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-23 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
1996-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df327a1297fb5809a639c08b95c701e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df6207325e7799699bf2f179c69e35bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f6c6b867834fe4548b53f1cd8c15d81 |
| publicationDate |
1997-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9715389-A1 |
| titleOfInvention |
Preparation of peptide containing biodegradable microspheres by melt process |
| abstract |
Peptide/protein biodegradable drug delivery devices are prepared as microspheres without the use of solvents by a polymer melt process. A melt of thermostable polypeptides and an appropriate low melting block copolymer mixture is prepared and dispersed in an appropriate fluid medium such as air, water or an immiscible organic fluid without using any organic solvent to form microdroplets. The fluid medium is cooled to solidify the microdroplets into microspheres and then collected and purified or further processed as drug delivery devices. These biodegradable microspheres are suitable as implantable or injectable pharmaceutical formulations. Following administration as solid microspheres into the body of a warm blooded animal, the formulations absorb water from the body to form a hydrogel from which the polypeptide is released continuously over an extended period of time. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6224793-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9173973-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9955454-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1034207-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1034207-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4656725-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889174-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1141079-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1141079-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020071912-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0188019-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002516910-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6262127-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010144178-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2809112-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-758475-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9724864-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002525404-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6083521-A |
| priorityDate |
1995-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |