| abstract |
A method for treating amyotrophic lateral sclerosis in a patient suffering therefrom comprising administering, directly into the central nervous system of said patient, ciliary neurotrophic factor, in a dose sufficient to maintain a measurable level of ciliary neurotrophic factor up to 1000 ng/ml in the cerebrospinal fluid, preferably 0.1-100 ng/ml, or a dose of hCNTF between 1-10,000 ng/day, preferably 250-1000 ng/day. |