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filingDate 1996-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1997-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9710810-A2
titleOfInvention Pharmaceutical granules
abstract A high speed agitation granulator method of preparing a substantially spherical granule for pharmaceutical use comprising a medicament for pharmaceutical use, wherein the medicament has an aqueous solubility of 0.01 to 0.30 g/ml, which method comprises introducing a mixture of medicament and excipients composing at least 5 % crystalline cellulose into the granulator and spraying on water or a mixture of ethanol and water as binder solution; a substantially spherical granule for pharmaceutical use comprising famciclovir and 5 % or more crystalline cellulose, together with an optional coating; and a sachet containing a unit dose of famciclovir in the form of such granules.
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