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filingDate 1996-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_412d2a6ebf132fe5351acb33724b35d6
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publicationDate 1997-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9707234-A1
titleOfInvention Process for producing optically active trans-2-bromoindan-1-ol
abstract A process comprising the step of treating trans-(+/-)-2-bromoindan-1-o1 in an organic solvent with a lipase originating in a yeast or a recombinant of the same; the step of selectively esterifying either the (+)-alcohol or the (-)-alcohol; and the step of separating the ester from the alcohol. Trans-2-Bromoindan-1-o1 of a high optical activity, which is useful as an intermediate of drugs, and its ester derivatives of a high optical activity are industrially and economically produced in high yields.
priorityDate 1995-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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