abstract |
A method of gene therapy in a human subject comprising administering to the subject a viral vector comprising a DNA molecule including a nucleic acid sequence encoding the genome of an ovine adenovirus capable of infecting human cells or functionally equivalent nucleic acid sequence or portion thereof and at least one nucleic acid sequence encoding a gene to be expressed in the cell, such that the viral vector infects at least one cell of the subject and the infected cell expresses the gene. |