abstract |
Tricyclic benzazepine compounds represented by general formula (I) and pharmacologically acceptable salts thereof. Because of having antiallergic effects, these compounds are useful in the treatment and prevention of bronchial asthma, eczema, urticaria, allergic gastrointestinal disorders, allergic rhinitis, allergic conjunctivitis, etc., wherein R represents hydrogen, substituted C1-6 alkyl or a protecting group; R?1, R2, R3 and R4¿ represent each hydrogen, hydroxy, substituted C¿1-4? alkyl, substituted C2-12 alkenyl, substituted C1-12 alkoxy or substituted amino. |