http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9640887-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d241434dd2e686fcc5aab7061164f8c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1317 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0677 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-00 |
| filingDate | 1996-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cea7cf418c71268eb15a4e25e884b18 |
| publicationDate | 1996-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9640887-A1 |
| titleOfInvention | Immunoprotective barrier for transplantation of cells |
| abstract | Cells for implantation into a patient in need thereof are packaged within an immunoprotective barrier prior to implantation, thereby obviating or minimizing rejection of the cells. The preferred immunoprivileged tissue for forming the barrier is cartilage. The tissue is formed into a layer that is thin enough to allow diffusion of nutrients and gases into the center of the cell mass placed within the immunoprotective barrier, typically less than 300 microns, preferably between 5 and 20 microns. Cells to be implanted, typically dissociated parenchymal cells including hepatocytes, Islets of Langerhans, or other cells having metabolic functions, are then placed on the barrier, and the barrier folded to seal the cells to be implanted within the barrier. In the preferred embodiment, the dissociated cells are first seeded onto a polymeric fiber matrix. The packaged cells are then implanted at a location providing an appropriate blood supply for diffusion of nutrients and gases through the barrier, for example, adjacent the mesentery. The example demonstrates packaging of Islets of Langerhans within a barrier formed by a monolayer of chondrocytes seeded onto polymer fibers. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7491388-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002529508-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100788800-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0029001-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9911220-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9314420-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011037865-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008002059-A1 |
| priorityDate | 1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.