| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_832999f230974e686160c11f3929678d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-30 |
| filingDate |
1996-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bf5a589443150543eb318e201719db4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_522e53943ceaa097964d472e24943ca9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68ba46cedd6edf2917b15660e8233b5f |
| publicationDate |
1996-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9640674-A1 |
| titleOfInvention |
Syntheses of optically pure compounds useful as garft inhibitors and their intermediates |
| abstract |
The invention relates to methods of making compounds of formula (VII) and their enantiomers, where Ar is a substituted or unsubstituted five- or six-membered aromatic group and B is either an amino acid linked through the amino portion to form an amide or a C1-C6 alcohol linked through the alcohol portion to form an ester. These compounds are advantageously employed as intermediates to prepare optically pure compounds that are active GARFT inhibitors. In one method, a compound of formula (III) or (XVII) is reacted with a compound of formula (IV), where X is a halogen. |
| priorityDate |
1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |