| abstract |
Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula (I), where R', R'', R''', R?x1, Rx2, Ry1, Ry2, Ry3, Ry4, and R0¿ are as defined in the description; R2 is formula (II); each R2a is independently hydroxy, halo, nitro, amino, trifluoromethyl, C¿1?-C6 alkyl, C1-C6 alkoxy or C1-C6 alkylthio; a is 1, 2, 3 or 4; R?3 is C¿1-C12 alkyl, C1-C12 alkoxy or -O-(CH2)m-[O-(CH2)n]p-O-(C1-C12 alkyl); m is 2, 3 or 4; n is 2, 3 or 4; and p is 0 or 1; or a pharmaceutically acceptable salt thereof. |