| abstract |
2-Hydroxyphenylalkylamine derivatives having the activity of inhibiting Maillard reaction and represented by general formula (I) and pharmacologically acceptable salts thereof: wherein R?1, R2, R3 and R4¿ may be the same or different and each represents hydrogen, lower alkyl, lower alkoxy, hydroxy, mercapto, halogeno, nitro, amino, acylamino, acyl or hydroxy(lower alkyl); R5 represents hydrogen or lower alkyl; A represents a single bond or lower alkylene or lower alkenylene optionally substituted by hydroxy; Y represents a single bond or lower alkylene; and Z represents carboxy, lower alkoxycarbonyl, aryloxycarbonyl, aralkyloxycarbonyl, carbamoyl, etc. |