http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9635426-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f332a12d7a2c85fda85e00180b413f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5820798e905665aff5fc670d6a60f6c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc2a22a9271507062ad7e07974d3c58 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
filingDate | 1996-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_913c7aee886fe4ab22a13bdd509a6fe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2704247dcc455d9d67cd7b0fe21dcd6f |
publicationDate | 1996-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9635426-A1 |
titleOfInvention | Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance |
abstract | In accordance with the present invention, it has been discovered that certain synthetic steroid compounds are capable of inhibiting the efflux pump which is believed to be responsible for multidrug resistance, while at the same time activating glucorticoid-induced response. Thus, chemotherapy of glucocorticoid sensitive tumors can be enhanced by use of a compound having the dual ability to activate glucocorticoid-induced response and facilitate the accumulation of drug at the target site, with reduced or eliminated competition by the drug efflux system. |
priorityDate | 1995-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 420.