| abstract |
The present invention provides a pharmaceutical exhibiting rapidly acting and sustained anti-inflammatory analgesic action against chronic arthritis, with low prevalence of side effects. A pharmaceutical comprising a combination of a quinoline/quinazoline-series prophylactic/therapeutic agent for arthritis and rapidly acting anti-inflammatory analgesics including (1) a cyclooxygenase inhibitor, (2) a central analgesic, (3) a steroid, or (4) an anti-inflammatory enzyme agent. Exhibits excellent effect against arthritis from initial stage of administration, ensuring stable anti-inflammatory analgesic action with low prevalence of side effects even in chronic administration, provided that drug combination, administration method and dose are appropriately chosen according to symptoms. |