| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e0a3e9578100cf105d929d0027b7ced
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b98fd36a210143abb9b0cd370eece0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_537ce7094e909428a3ac2d3f2bd941d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3d5fd5e26b7afbb813953cede224067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a494a8968e66fea2a0ef50933321e189
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b50828dd632c27d4f64e714a983d5e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72f181d087d9e0390771849d958d508 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-08 |
| filingDate |
1996-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9bef799a5c757ff8579d50fc634c71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27d62796536133be7011d721a11c806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c4617fed8e7e750e18f388b449e877f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e8ff79c3683c5d98989625b3a8d8d54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3420633328f6cb8a294206e2fe0d3094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6b22dac0ef3b9ca011e04f076cf0611 |
| publicationDate |
1996-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9629334-A1 |
| titleOfInvention |
PROCESSES FOR THE PREPARATION OF β-LACTAM DERIVATIVE |
| abstract |
A process for the preparation of an allenyl-β-lactam compound which comprises reacting the hydroxyl group of a β-lactam compound of general formula (1) with a reactive functional derivative of a sulfonic acid of the general formula (2): R5-SO2-X to form a β-lactam compound of general formula (3) and reacting the formed compound with a basic anion-exchange resin containing a tertiary organic base immobilized thereon to attain the preparation of an allenyl-β-lactam compound of general formula (4) and the stable isolation thereof from the reaction mixture in a high yield at a high purity. Another process for the preparation of an allenyl-β-lactam compound which comprises reacting the hydroxyl group of a β-lactam compound of general formula (1) with a reactive functional derivative of a sulfonic acid of the general formula (2): R5-SO2-X to form a β-lactam compound of general formula (3), reacting the formed compound with a tertiary organic base to form an allenyl-β-lactam compound of general formula (4) and treating the resulting reaction mixture with both an acidic cation-exchange resin and a basic anion-exchange resin either alternately or simultaneously to isolate the compound of general formula (4) from the reaction mixture stably. A process of preparing a 3-halocephem derivative of general formula (6) by reacting an allenyl-β-lactam compound of general formula (4) with a halogenating agent in the presence of a sulfinate or thiolate ion scavenger. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2325227-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2325227-A |
| priorityDate |
1995-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |