| abstract |
A method of inhibiting viruses in which a virus is contacted with an antiviral amount of a compound of formula (I). Activity is shown against HIV and other viruses. In formula (I), W is a bridge carbon which has a polar or non-polar side group; X and Y independently are an aromatic group, an alkyl group, a sulfonyl group or a carbonyl group, said aromatic group is selected from the group consisting of Ar, Ar sulfonyl, Ar carboxy and Ar alkyl, where Ar is an aromatic cyclic or aromatic heterocyclic ring having from five to seven members; said alkyl group having from one to ten carbons; Z is a group listed for X and Y, a fused aryl moiety having from seven to ten carbons or hydrogen; a, d and e independently are a number from zero to 10; c and b independently are a number from one to 10; and the formula is cyclic or acyclic and includes sufficient hydrogens for a stable molecule. |