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filingDate 1996-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1085c536aaff328eab7ab349060d006e
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publicationDate 1996-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9622958-A1
titleOfInvention Process for the production of 2-(substituted benzoyl)1,3 cyclohexanediones
abstract A process for preparing a compound of formula (I), where R?1, R2, R3, R4, R5 and R6¿ are independently hydrogen or C¿1-6? alkyl; R?7¿ is halogen, cyano, NO¿2?, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy or RaS in which Ra is C1-4 alkyl; R?8, R9 and R10¿ independently are hydrogen, halogen, C¿1-4? alkyl, C1-4 alkoxy, C1-4 haloalkyl, C1-4 haloalkoxy, CN, NO2, phenoxy or substituted phenoxy; RbS(O)n Om in which m is 0 or 1, n is 0, 1 or 2 and Rb is C1-4 alkyl, C1-4 haloalkyl, phenyl or benzyl, NHCORc in which Rc is C1-4 alkyl, NRdRe in which Rd and Re indenpendently are hydrogen or C1-4 alkyl; RfC(O)- in which Rf is hydrogen, C1-4 alkyl, C1-4 haloalkyl or C1-4 alkoxy; SO2NRgRh in which Rg and Rh independently are hydrogen or C1-4 alkyl; or any two of R?8, R9 and R10¿ together with the carbon atoms to which they are attached form a 5 or 6 membered heterocyclic ring containing up to three heteroatoms selected from O, N or S and which may be optionally substituted by =NOC¿1-4? alkyl, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy or halogen; which process comprises the rearrangement of a compound of formula (II) where R?1, R2, R3, R4, R5, R6, R7, R8, R9 and R10¿ are as defined in relation to formula (I), in a non-polar solvent in the presence of a cyanide source, an alkali or alkaline earth metal carbonate, a phase transfer catalyst and 1-6 moles of water with respect to the compound of formula (II).
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priorityDate 1995-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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