http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9620697-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_111ec27d2e874cd8c4b404ff4f39f89d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 1995-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_066a2f7f7e039052824633be9981d078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_643f346a64f2fa29329903901fb2ca14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af345830552f1a16de2b62cd779d7911 |
| publicationDate | 1996-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9620697-A1 |
| titleOfInvention | Terfenadine oral granules |
| abstract | The present invention contemplates a dry, granular terfenadine composition. That composition comprises (i) particulate terfenadine and (ii) a polyethylene oxide-polypropylene oxide-polyethylene oxide block copolymer having an HLB number of 24 that is a wetting agent for the terfenadine that are dry-blendedly dispersed onto (iii) spray-dried sorbitol particles that are loosely packed, randomly oriented filamentary crystals having pores that entrap the particulate terfenadine and wetting agent upon the dry-blended dispersal. The weight ratio of particulate terfenadine to the block copolymer is about 1:1 to about 1:5:1, and the weight ratio of terfenadine to the spray-dried sorbitol is about 1:4 to about 1:10. The composition is free-flowing and is substantially free from the taste of solubilized terfenadine when placed on the human tongue in dry form or when dispersed in water and tasted within about five minutes of said dispersal. A preferred composition further includes dry-blendedly admixed polyvinylpyrrolidone present in an amont of about 0.5 to about 5 weight percent of the total composition. Flavorants can also be present. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1025858-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1025858-A1 |
| priorityDate | 1995-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.